PSA: You can lock yourself out of Cyberpunk 2077: Phantom Liberty's main questline early on

pcgamer.com:

Cyberpunk 2077: Phantom Liberty is a preem spy thriller adventure. However, if your V really isn't that interested in working with government types, you can choose not to sign on to a life of martinis shaken, not stirred.

Only issue is, choosing to do so locks you out of the questline—and from what I've tested, it's permanent. At minimum it'll delay your progression through the DLC's story substantially, but I don't get the sense Reed's gonna call me back.

Here's the mostly spoiler-free rundown: at the end of a mission called Lucretia My Reflection, you'll be given a choice to stay or go. If you go, you really do go—you fail the mission, and are roadblocked from proceeding. 

You can still run around Dogtown, but there'll be no suit and tie galas with Mr. Elba, which is a crime in itself. Just make sure to play ball with your new friends, and you'll be golden. If you're really worried about accidentally dropping the new DLC, here's the specifics.

Lucretia My Reflection is the fourth mission in the DLC's main questline, a couple of hours into the DLC's fairly opening gauntlet. The missions before it are, in order, Dog Eat Dog, Hole in the Sky, and Spider and Fly.

To save you the anxiety of accidentally flipping off the FIA, you'll want to start paying attention when Reed reunites with NUSA President Rosalind Myers. While the two stand in front of a gloomily lit, blinded window (in true pulp noir fashion), you'll be given a choice to say «You're right, I'm out». 

This isn't immediately binding, and the game gives you a chance to stick with the plan. President Myers warns you «Walk out of here, and the deal's null and void—understand?» If you select the option «Made my decision», you'll fail the quest completely and be left