There's absolutely no way the Spider-Man: Freshman Year animated series can be part of the main MCU canon timeline. When Marvel first announced Spider-Man: Freshman Year as part of the inaugural Disney+ Day, it was presented as though it was part of the main MCU timeline. This, it seemed, would be the definitive Spider-Man origin story the MCU had avoided — the tale of how Peter Parker became the character introduced in Captain America: Civil War.
Disney press releases have reinforced the point, with a standard line explaining the show is "an animated series that follows Peter Parker on his way to becoming Spider-Man in the MCU, with a journey unlike we've ever seen and a style that celebrates the character's early comic book roots." The SDCC 2022 Marvel Animation panel revealed Spider-Man: Freshman Year, which will air in 2024, will feature a wide range of supporting characters — including Harry Osborn, Daredevil, Doctor Strange, and comic book superheroes Amadeus Cho and Nico Minoru. Even more surprisingly, Spider-Man: Freshman Year will feature villains such as the Rhino, the Chameleon, Speed Demon, Doctor Octopus, Norman Osborn, and the Scorpion.
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These various cameos mean there's simply no way to reconcile Spider-Man: Freshman Year with the main MCU timeline. There are too many contradictions; Vulture was supposed to be Spider-Man's first supervillain in Spider-Man: Homecoming, and the MCU's version of the Scorpion — Mac Gargan, played by Michael Mando — didn't look anything like the one teased at the panel. In the MCU, Spider-Man was only introduced to Doctor Strange in Avengers: Infinity War — with a customary name gag because he thought the sorcerer's
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