The Cyclops Polyphemus appears on your path to the Surface in as a powerful boss that can be extremely difficult to beat if you're unprepared. This giant enemy uses sheer physical strength to end your run as quickly as it began, especially if you don't have the right tools. You need to gather important bonuses along your path to Polyphemus to stand a chance against his might.
Unlike many of the boss fights against other opponents, such as Headmistress Hecate in , Polyphemus has phases to his battle. There will be a clear time when an aspect of the fight shifts, instead of the boss just using new moves when their health gets low. This forces you to form two strategies that blend to form a consistent and singular plan that will overcome both phases equally.
Polyphemus is encountered on the path to Olympus as the first boss you fight in Ephyra, the first settlement you reach on the Surface.
The List of Minor Prophecies in Hades 2 is a questboard that gives various side objectives with decent rewards, along with an entirely new character.
The best weapons to use against Polyphemus are the Witch's Staff or Argent Skull due to their ability to attack over a distance with ranged magic. The Cyclops' greatest strength comes from their close-range melee strikes, which deal so much damage that they could one-shot Melinoë in . Having weapons that don't force you to close distance to this boss gives you more chances to stay away from their attacks.
The Witch's Staff is a well-rounded weapon you start with at the beginning of the game that can do physical strikes and special projectile moves in tandem. This weapon gives you more freedom to adapt to Polyphemus, but those looking to specialize in only ranged attacks should stick to the Argent Skull. The Skull has limited ammo but packs more of a punch with heavy damage on top of a deadly dash attack.
Some weapons Melinoë has in must be crafted using rare materials. For example, the Moonstone Axe takes 15 Silver to create,
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