For the most part, the remake has remained faithful to the original game, but one surprising change makes it impossible to kill a previously mortal character. Although murdering this NPC only made things harder for Leon in the long run, and it didn't have any feasible impact on the overarching narrative, it served as an entertaining outlet for chaos in the original version of the game. For some reason, this possibility is now eliminated in a strange remake change.
In the grand scheme of things, the merchant suddenly becoming untouchable is likely one of the last adjustments that players will notice. After all, besides the obvious improvement to graphics and performance, many of 's gameplay and story features received much-needed overhauls. For one, Leon's knife is now breakable, meaning players won't be able to rely on their melee weapon as much (but the tradeoff is a satisfying parry system). Other tweaks, like the removal of QTEs and the addition of charms also set the remake apart from the original — but making the merchant unkillable strays from its predecessor in a big way.
Related: Resident Evil 4 Remake Mercenaries DLC — Release Date, Platforms, & Price
It's no longer possible to kill the Merchant in the remake. In fact, Leon refuses to even aim his weapon at him, signifying his new status as an essential NPC. This was not the case in the original version of the game, wherein it was possible to shoot or slice the Merchant to death, even though he would almost always reappear in a different area on the map. This sparked some interesting theories about the nature of the character, suggesting that there were several different Merchants as opposed to one — but since he can no longer die, this theory inherently
Read more on screenrant.com