While Loki and Spider-Man: No Way Home opened the door to the multiverse's existence in the MCU, Doctor Strange in the Multiverse of Madness will break it wide open and change the landscape of the MCU forever. The heroes of this universe will soon learn He Who Remains isn't the only one who has «less pure of heart» variants. Stephen Strange and Wanda Maximoff will come face to face with their own variants in the Doctor Strange sequel and take on a whole new meaning of self-discovery. However, even this prospect is far from the film's most chaotic.
The events of Loki and Spider-Man: No Way Home combined with whatever shenanigans Doctor Strange and Scarlet Witch concoct in Doctor Strange 2 will change the landscape of the MCU as we know it. In the simplest terms, Marvel Studios could make movies that take place in entirely different universes, building on the trend started by Ta Lo in Shang-Chi and the Legend of the Ten Rings. Movies like the next Fantastic Four reboot or future projects involving mutants could take a similar approach and be set in a universe adjacent to the original MCU timeline, and that is just the tip of the iceberg.
Related: Multiverse of Madness Theory: How Doctor Strange Breaks The Multiverse
The trailers and poster for Doctor Strange 2 hint at the debut of the Illuminati, mutants, and multiversal characters Doctor Strange Supreme and Captain Carter from the Disney+ What If…?series. Furthermore, without the Time Variance Authority around, what Doctor Strange (or Wanda) does to cause such multiversal chaos could have far-reaching consequences. Consequences that He Who Remains's variants would be more than happy to exploit. Here's how the events of Doctor Strange 2 could have lasting effects on the
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