During their Season 2 developer stream, Blizzard has showcased new vampiric monster families joining the fray of enemies, adding further chaos to the world of Sanctuary. Controlled by Lord Zir, the season's main story antagonist, these new enemies can most certainly be met in Blood Harvests and other seasonal-related content types.
Another addition to the pool of enemies will be the so-called Blood Seekers, player-looking creatures much more powerful than the average minion controlled by the vampire lord.
Expanding on the addition of these new monster families, the Diablo 4 development team stated that their abilities will involve more «area denial» and that players «should definitely watch where they step». Some of the new enemies will also have new after-death effects like lumps of blood which will shield other enemies around them, so players might want to adjust their target priorities.
Diablo 4 Season 2 Developer Update Liveblog Who Are The Bloodseeker Lieutenants in Season 2