Catherine the Great is one of the best leaders in for a Cultural Victory due to her Star of the North ability, which boosts Culture from Great Works and allows her to advance Technology research alongside Cultural growth. This will be a highlight of Catherine the Great's campaign strategy, as a Cultural Victory hinges on strong Production (especially during the Antiquity Age), as well as Science to ensure access to the best Food, Production, and Culture buildings. To achieve the Cultural Victory, Catherine the Great's best options are Greece in Antiquity, Norman in Exploration, and Russia in the Modern Age.
Each of these civilizations complements Catherine the Great's ability and will allow her to take full advantage of both Culture and Science yields during each Age. The Cultural Victory in includes the Wonders of the Ancient World, Toshakhana, and Geographic Society Legacy Paths, which Catherine will have no trouble completing in a timely fashion. With these civilizations, she will also be capable of developing a powerful defensive Army, and will have sufficient Influence to build alliances and become Suzerain of City-States. Overall, Catherine the Great is a well-rounded leader in who can easily achieve a Cultural Victory.
Catherine the Great can set up for the Wonders of the Ancient World Legacy Path with high Production output in the capital city and by leveraging Cultural City-States and other Wonder-boosting options to crank out Wonders quickly. To take full advantage of her unique ability, aim to acquire Codices (Antiquity Age Great Works) by befriending Science City-States, mastering Technologies, building the Nalanda Wonder, etc. Science will not be in short supply, assuming Greece's capital is placed in Tundra. Consider strategic Settlements placed in Tundra throughout the entire campaign, as Russia will benefit greatly from these in the Modern Age.
The Eagle Banner Memento synergizes really well with Catherine the Great's leader ability, increasing
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