Tony Stark once pointed out a considerable flaw with The Flash's speed powers, as Iron Man admitted that not only did they not make any sense from his perspective, but they wouldn't work the same in his universe. In JLA/Avengers #3 from Marvel and DC Comics, the heroes worked together in an epic crossover, as Stark watched Barry Allen use the cosmic treadmill. However, he quickly realized that his powers might not be useable in certain worlds since different physics would prevent him from accessing them.
The Flash's powers come from the Speed Force, an extradimensional energy source granting the hero a wide array of abilities, including super-speed, energy manipulation, and even a healing factor. By tapping into the Speed Force and his super-speed, The Flash and certain powerful speedsters can also travel through time and different realities with the Cosmic Treadmill. However, when Iron Man first saw the time-traveling device in action, he pointed out a considerable flaw that would happen if Flash tried to use it in the Marvel Universe as opposed to the DC Comics reality he's from.
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In JLA/Avengers #4 by Kurt Busiek, George Perez, Tom Smith, and Comicraft, the Justice League and Avengers worked together to restore reality and take on the villain Krona, who has merged the DC and Marvel Universe — causing the world around them to change continually. Iron Man and The Flash concoct a plan to get to Krona's stronghold, using Thor's hammer Mjolnir and the Cosmic Treadmill to break through his shields. However, when they combine their powers, Tony Stark points out that the Flash's speed time-travel powers have one considerable flaw: they wouldn't work
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