Warning: The following contains SPOILERS for Morbius
A cameo from the Vulture (Michael Keaton) in Morbius suggests that Sony's Spider-Man universe truly is building toward the introduction of the Sinister Six. In Marvel Comics, the Sinister Six is a team of Spider-Man's biggest villains whose primary goal is to bring down their greatest nemesis. The team was originally formed in the 1960s when Doctor Octopus, Electro, Kraven the Hunter, Mysterio, Sandman, and Vulture decide that since they can't beat Spider-Man alone, an alliance between the six of them could bring Spider-Man to his knees. Fifty years later, they remain one of the most popular villain teams in the comics, which is why fans have been eagerly anticipating their live-action debut.
Perhaps the biggest takeaway from Morbius is the reveal that it takes place in the Marvel Cinematic Universe. Apparently, this goes for Venom and its sequel as well. When Venom was in production, there was much talk over whether or not the film was set in the MCU, and contradicting comments made it unclear. It was eventually understood that Venom existed outside of the MCU and instead served as the first installment in Sony's Marvel Universe, a cinematic universe which only includes Spider-Man characters owned by Sony.
Related: Morbius and New Mutants Crossing Over Into Horror Is Smart For Superhero Movies
Morbius changes everything by confirming that it and Venom share the same world as the MCU. A scene where Spider-Man is labeled as a "murderer" clearly acknowledges the cliffhanger ending of Spider-Man: Far From Home. Also, Vulture from Spider-Man: Homecoming appears at the end of the movie, erasing any lingering doubts about the integration of Sony's Marvel Universe into the
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