Warning: Contains SPOILERS for Doctor Strange in the Multiverse of Madness
Doctor Strange in the Multiverse of Madness indicates that the heroic sorcerer remembers web-slinger Peter Parker in a specific way after Spider-Man: No Way Home's ending. In Sam Raimi's horror-influenced Multiverse of Madness, Doctor Stephen Strange (Benedict Cumberbatch) must stop the Multiverse rampage of the Dark Hold-wielding Scarlet Witch (Elizabeth Olsen). America Chavez (Xochitl Gomez), who has the ability to transverse from one universe to another, is Wanda's target in the film. An early scene gives some hints to how Doctor Strange's memory wiping spell in No Way Home worked in eliminating all memory of Peter Parker from the world to stop numerous universes from opening into the MCU.
When Strange and Wong (Benedict Wong) meet America in a café, Strange mentions a previous Multiverse incident involving Spider-Man, which obviously refers to the events of No Way Home. This also provides some context to how Strange's spell functioned, and how he himself was affected by it. In a nutshell, the world and Strange have forgotten about Peter Parker (Tom Holland), while their knowledge of Spider-Man remains intact.
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By referencing the existence of Spider-Man and the story of No Way Home as a Multiverse movie, it can be concluded that Strange remembers Spidey and the general events of No Way Home that they experienced together. What's changed is his knowledge that it's Peter under the mask. No Way Home was predicated on the public learning Spider-Man's identity in Spider-Man: Far From Home. With Peter and Strange's efforts to undo that with his spell, and everything that came
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