The Hystrix Prime is a Secondary Pistol in Waframe that serves as the Primed variant of the Hystrix, Khora's Signature Sidearm capable of firing metallic quills. Likewise, the Hystrix Prime is Khora Prime's Signature Weapon, alongside the Dual Keres Prime. This enhanced Secondary Pistol features bolstered Damage, Critical Chance, Reload Speed, and Status infliction on enemy targets. Accordingly, Tenno can use Hystrix Prime weapon in Warframe to use Alternate Fire, inflicting mobs with Heat-, Ice-, Electricity-, and Toxin-Elemental quills.
Because the Hystrix Prime lacks magazine size, its user will likely need to reload frequently due to its high rate of fire. Furthermore, the projectiles travel slower than normal bullet projectiles, meaning that timing and positioning are crucial when firing. Nevertheless, this Primed Pistol is still a formidable weapon thanks to its high Critical Chance and above-average Crit multiplier. Moreover, equipping Khora Prime with this weapon will grant her an 8% bonus chance to instantly reload when successfully landing a headshot on an enemy target.
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To unlock Hystrix Prime in Waframe, players must farm Hystrix Prime Relics to procure the weapon's required drops. These drops include the Hystrix Prime Blueprint, Hystrix Prime Receiver, and Hystrix Prime Handle. Each of these items in Warframe drops from a specific Relic, meaning that Tenno must farm the Relic until they receive the item drop they need.
First, Tenno must farm Neo G4 Relics, which has a Common 25.33% chance of dropping the item to get Hystrix Prime Blueprint for the Prime Secondary Pistol. Next, the Hystrix Prime Receiver comes from the Meso H3 Relic, featuring a Rare
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