Boruto: What Is The Kara Clan?

gamerant.com:

Naruto featured the complex villain organization, Akatsuki, comprising a bunch of interesting characters like the sly scientist Orochimaru, the powerful and vengeful Uchiha Madara, and Nagato Uzumaki, popularly known as 'Pain.' Boruto: Naruto Next Generations, on the other hand, is set in a post-war and peaceful era, with Boruto Uzumaki at its epicenter.

However, despite the new peaceful era, trouble soon arises, spearheaded by the Kara Clan, an organization comprised of human cyborgs and an Otsutsuki – a powerful force similar to Kaguya Otsutsuki that played a crucial role in the Fourth Great Ninja War. Either way, the Kara Clan is a threatening existence to the Village of the Hidden Leaf and the World.

How Much Has Boruto Changed Since Season 1?

The organization Kara was first mentioned in Chapter 15 of Boruto manga after Boruto's mysterious seal on his hands surfaced during his fight with a rogue ninja. Even after the villain's defeat,Boruto revealed little information about 'Kara’ until later on in the series, when Kawaki – Jigen’s vessel, or rather the actual vessel for Isshiki met Boruto. Readers then discovered that the connecting factor between the Kara Clan and Kawaki has to do with 'Karma.' According to Amado, Karma is the compressed form of the Otsutsuski's memory which they place on humans they call «vessels» for them to resurrect from those humans using their parasitic implant.

Later on in the series, the manga showed the goal of the Kara Clan to be the revival of a divine tree, with a Jyuubi at its root, to create a Chakra Fruit by wiping out life from the earth. Despite Isshiki's defeat with the aid of Naruto's Baryon Mode, the Otsutsuki will still live on, especially through the scientifically enhanced human