The Isu were the highly advanced precursor civilization in the Assassin's Creed series that were responsible for making the Pieces of Eden, creating humanity, and leaving messages behind to help save the Earth from destruction. There are different factions of the Isu that were recognized throughout history as Gods in Roman, Egyptian, Norse, and other mythologies. There isn't much known about the origins of the Isu, but there are a number of beings that influenced history and some of the major events and characters in Assassin's Creed.
The Isu made humanity in their image but created them by genetically altering a hominid species to ensure their obedience. Humans were created and used for slave labor, and Neanderthals were made to be a military force. Eventually, a human rebellion formed, plunging the world into war, which distracted the Isu from the impending threat of a coronal mass ejection from the sun. After the Great Catastrophe, most of the Isu were gone either right away or shortly after.
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The Isu were mentioned as early as the first Assassin's Creed. However, the first appearance occurred in Assassin's Creed 2 when a projection of Minerva spoke to Ezio in the Vatican Vault. With the latest release, Assassin's Creed Valhalla, the Gods from Norse mythology, and a few from the Celtic pantheon, were added to the list of known Isu.
The Gods that make up the Greek, Etruscan, and Roman pantheons are some of the most significant and frequently mentioned Isu of the precursor civilization in Assassin's Creed. Many of them have different names depending on which religious group they're recognized by. However, each of the different names represents the
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