How The Destroy Ending Impacts Every Major Mass Effect 4 Race

gamerant.com:

With Mass Effect 4, or whatever BioWare properly titles it, the company also had a major decision to make. Would it, in essence, make Mass Effect: Andromeda 2—another story largely disconnected from the events of the main trilogy—or would it somehow follow the events of the Milky Way galaxy, even if this means canonizing certain events?

For now, all signs point toward some culmination of the two, as Mass Effect 4 seems to canonize the Destroy Ending, is connecting the Andromeda and Milky Way galaxies in some way, and likely features some form of time skip.

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The latter appears likely, as not only does the Milky Way have to recover from the Reaper invasion, but one Mass Effect 4 trailer seemingly shows off an older Liara. That's not to mention how much time it takes for the original Initiative to get to Andromeda. Thus, the biggest question is how the various races introduced throughout the franchise have grown and changed in the wake of the Reaper Invasion. While largely speculation at this time, there are enough hints based on in-game events to suggest the general direction the races played after their release.

Although these races are not impacted by the Reaper Invasion, the Andromeda Galaxy’s importance to Mass Effect 4 makes the aftermath of the game just as important. The exact impact and time passage as it relates to Andromeda remains to be seen, but the Angara learn more of their culture and history. It’s likely there are more secrets to be revealed, especially in their relationship to the Remnant and Jardaan. It’s hard to see how these mysteries don’t play a major role in the new game.

The Kett, on the other hand, may be largely defeated in the