One of the best things about Fallout 3 is how there is a bunch of little societies all over the wasteland. As such, you probably won't meet some of them during your travels. However, it's worth going out of your way to link up with the people of Big Town.
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This is because they provide you with the Big Trouble In Big Town quest, and you earn an achievement or trophy for completing it. The mission revolves around helping the people of the town in their conflict with a nearby gang of Super Mutants. This is everything you need to do to lend a hand.
This quest can be started in either of the following ways:
Regardless of how you begin the quest, you have to head to the Germantown Police HQ to rescue Red. The place is north of Big Town, the Merserti Trainyard, Hollowed Moors Cemetary, and Agatha's House. Plus, it's slightly west of a minefield that gets marked on the map.
Once you're there, you must watch out for any Super Mutants that are roaming around. Red is being held inside the main building, which has two entrances.
One option is to use the door on the north side of the area. To reach it, you must climb up the stairs of a ruined building. Once you're inside, you need to find your way to the ground floor while watching out for any Super Mutants or mines.
If you don't know how to get there, you can follow this path:
Now that you're on the ground floor, you must locate the room with Red's cell. To do that, follow this route:
Alternatively, you can use the door on the west side of the Police HQ. However, your lockpick skill needs to be at least 100 to unlock the thing. If you can get through it, though, you can simply enter the first room on your left to locate Red's
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