Farming bosses in has been the definitive endgame experience for a while now, which has not changed with the release of the expansion. While these bosses don't drop Legendary gear anymore, they now only drop Unique items, which makes it far easier to target specific pieces of gear. And with the addition of Runewords this season, Tormented Bosses have become more important than ever.
Last season, all it took was four Resplendent Sparks to craft any Mythic Unique item of your choice. However, this has been reworked in order to incorporate the addition of Runes. Mythic Uniques now require three different sets of Runes in order to craft, with the three types necessary being different depending on the Mythic crafted. In order to obtain enough Runes to craft the desired Mythic, players should prioritize farming Tormented Bosses in .
While all Tormented Bosses have a chance to drop Mythic Unique items, Duriel and Andariel have double the chance than all other bosses do. This means that it's most efficient to farm Mythic Unique items from these bosses, as opposed to trying your luck from a boss like Grigoire, The Galvanic Saint. Different Tormented Bosses will drop different loot depending upon the class you are playing, except for the Rogue who has no Mythic Unique gear tied to their class.
Class
Mythic Uniques
Barbarian
The Grandfather
Druid
Ahavarion, Spear of Lycander
Necromancer
The Grandfather
Sorcerer
Ahavarion, Spear of Lycander
Spiritborn
Nesekem, the Herald
All Classes
Doombringer Melted Heart of Selig Andariel's Visage Harlequin Crest Ring of Starless Skies Tyrael's Might Heir of Perdition Shroud of False Death Shattered Vow
Tormented Bosses also have a high chance to drop a variety of Runes, which can be used to craft specific Mythic Unique items at the Jeweler vendor. Each Mythic Unique will require three different sets of Runes to craft, of which six per set are needed. For example, in order to craft Tyrael's Might, the player needs six Lith Runes, six
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