The Witcher 3 features multiple open-world areas with lots of characters and quests to discover in each of them. Some quests are necessary to complete the main questline, while others have standalone side missions with unique stories and locations.
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A Towerful Of Mice is a quest that relates to Keira Metz, who is one of Geralt's magical associates. You can complete multiple quests for Keira Metz, and A Towerful Of Mice is in the middle of
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