When it comes to Resident Evil, the spirit of villainy is in the name. Across dozens of mainline games and spinoffs, we’ve come face to face with a number of truly terrifying individuals, be they mutants, cult leaders, or corporate operators. But who can be considered the ‘most’ evil of them all? We’ve ranked the 10 worst of the worst right here, so read on if you dare.
Note: While we won’t be spoiling anything too dramatic, you’ll probably want to have played the games before reading further if you’re worried about spoilers.
10. Oswell E. SpencerOswell is only seen in the flesh in Resident Evil 5, but his looming presence is felt in every game in the series. Oswell is the president of Umbrella, the company responsible for the disasters that run throughout the entire series’ history. He’s even the one who inspired Mother Miranda to conduct her mold experiments that led to the events of Resident Evil 7 and Village.
Related: What does Resident Evil Village: Gold Edition include? – New modes, new Mercenaries characters, and more
9. Jack KrauserWhen he first appeared in Resident Evil 4, it was clear that Krauser had a history with hero Leon Kennedy. Darkside Chronicles digs deeper into that, but 4 threw the two of them together in an intense knife fight. Screw up even once, and Leon would be stabbed to death. If that wasn’t enough, Krauser returns later for a second fight in which his arm has mutated into a giant wing that serves as both a shield and a sword.
8. Osmund SaddlerSaddler was also introduced in Resident Evil 4 as the leader of the Los Iluminados cult. He’s responsible for the kidnapping of the president’s daughter Ashley Graham and for injecting his people with the deadly Las Plagas parasite. He also gets
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