The Omega Ruins are one of the toughest areas in Final Fantasy 10, containing some of the strongest enemies and bosses in the entire game. The opponents you face here will reduce your health to zero in a hurry if you aren't prepared to face them.
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You can access this location in Final Fantasy 10's late-game after you unlock the airship. But, before you begin, make sure you've leveled up enough and are happy with your equipment. You can return to the airship after completing the game's last dungeon, Inside Sin, so use that as an opportunity to grind if you need to.
Once you've unlocked the game's airship, you can enter coordinates to reach secret locations. Enter the coordinates X72, Y35 to reach the Omega Ruins. Since there's only one save point at the start of the dungeon, grind against some enemies near the entrance until you feel confident you can progress. Otherwise, you'll waste a lot of progress mid-way through.
The Omega Ruins are home to two bosses, Ultima Weapon and Omega Weapon, as well as an RNG-based chest mini-game.
The enemies in the Omega Ruins can put up a tough fight, especially if you've not prepared beforehand. The Great Malboro will always ambush players and will always cast Bad Breath, a move that inflicts various ailments such as confusion, berserk, silence, poison, and slow. It's certain death for unprepared players. Having First Strike equipped on a party member's weapon will allow you to strike first, even when an enemy ambushes you, allowing you to summon an Aeon with Yuna, or deal with the Great Malboro before it casts Bad Breath. Having confuseproof equipped on a piece of equipment is also a viable strategy.
Master Tonberry is another enemy
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