As the Twelfth Divison Captain and leader of the Shinigami Research and Development Institute in Bleach, the Gotei 13 have certainly bestowed a great deal of faith upon Mayuri Kurotsuchi's capabilities.
This scientific mind may not have spent a great deal of energy on mastering his sword fighting techniques, however, he makes up for these substandard skills with his genius-level intellect and unashamed ingenuity. And once a greater understanding of his Zanpakuto is achieved, it becomes clear that Mayuri never needed to excel at dueling in the first place; for him, it is always a battle of the wits.
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Mayuri's Zanpakuto goes by the name of Ashisogi Jizō (which translates as "The Leg-Cutting Guardian"), but this beast can do much more than sever limbs. When its Shikai form is activated as Mayuri says "Rip," this blade transforms into a warped trident with a guard shaped like a baby's head, which intermittently discharges puffs of poison into the air. Those unfortunate enough to get stabbed by one of Ashisogi Jizō's three prongs will immediately succumb to paralysis as the communication between their brain and their neural impulses are broken down by the poison damage.
The point of this Zanpakuto's contact is irrelevant; Mayuri's opponent will be incapable of using their limbs (specifically) regardless of the wound's position, and healing the laceration will not negate their immobility either. To make matters worse,the pain receptors are subsequently elevated to the max, leaving the unfortunate recipient fully aware of every agonizing injury (including the paralyzes parts.) Being the sadist that he is, Mayuri often uses this nifty feature to torture his victims
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