Intel introduced its first hybrid desktop CPU architecture with a mix of Performance and Efficient cores, known as Alder Lake, back in late 2021. AMD isn't expected to offer its own hybrid CPU for consumers and gamers until Zen 6 arrives and so probably not until 2026.
However, AMD has engineered some new smaller cores roughly equivalent to Intel's E-cores, known as Zen 4c, and they could be quite a bit more powerful than Intel’s.
Semianalysis has a deep dive on 4c and there are a few take-away highlights. First, AMD's small cores are bigger. Intel fits roughly four Efficiency cores into the space of one Performance core. AMD's Zen 4c cores are about half the size of full Zen 4 cores, as found in its latest Ryzen 7000 CPUs.
More broadly, Zen 4c seems to be functionally much closer to a full Zen 4 core, but rearchitected for efficiency. Apparently, just redesigning the cores to a lower clockspeed target allows the core to be much smaller without losing any functionality.
AMD's Zen 4c cores also support multi-threading, with two threads per core just like Zen 4. Intel's Efficient cores, on the other hand, don't have multi-threading support. The net result is that you can probably expect the IPC on Zen 4c cores to be a lot closer to Zen 4 than Intel’s E-core IPC gets to its Performance cores.
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The caveat to all this is that AMD's small cores are years away from being introduced in gaming PCs. By the time Zen 6 CPUs roll out, Intel will have iterated its Efficient cores a few times.
But this early look at Zen 4c implies that Intel's small cores will face some stiff competition. It also suggests that Intel and AMD
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