Though the spirit and mortal worlds are frequently depicted as being separate and located on their own planes of existence, there are many stories that have them clashing. The journey of Nioh 2 has you and any warriors you join going on missions to destroy any sources of evil, be they mortal or spirit.
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Though you'll fight both human and Yokai enemies, it's not uncommon for these beings to combine forces to pose a much more dangerous threat. An example would be the boss enemy Minamoto No Yoshitsune, a human-yokai hybrid that you'll encounter in both forms and be tasked with eliminating.
The game's lore describes this being as a skilled swordsman and military leader. Being a part of the main story, he joined the army in order to fight against the Taira clan. While on your own campaign, you'll run into Yoshitsune multiple times and team up with him to battle mutual enemies.
Unfortunately, you two will eventually come across and horrifying and upsetting sight that changes Yoshitsune to the core. It causes him to transform into an Aratama, a Yokai known as a savage spirit. In this state, he'll be beyond reason, and you'll have no choice but to defend yourself. Yoshitsune can be fought in the Main Mission of Eternal Rivals and the Sub Mission of Bond Of The Blade. It's recommended that you be at levels 124 and 129, respectively.
Yoshitsune is a highly-trained swordsman with Yokai powers, so he will not be easy to defeat. His altered form gives him resistance to Paralysis, Lightning, Fire, Water, and Poison damage. He also possesses immunities to being Saturated, Scorched, and Shocked.
For effective attacks, have a good source of Purity and Corruption options
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