In the Netflix series Uncoupled, Michael (Neil Patrick Harris) briefly dates a dermatologist until the doctor unexpectedly suggests Botoxing Michael's butthole to facilitate sex, prompting the question of whether this is an actual practice. Michael is often caught off-guard during the series by contemporary sexual practices because, in a reversal of Neil Patrick Harris' role of Barney in How I Met Your Mother, Michael has not been part of the dating scene in 17 years. The Botox incident could be read as an exaggerated example of him being freaked out by unexpected attitudes around sex and not necessarily a real thing–or is it?
Following Michael’s breakup with Colin (Tuc Watkins), Michael’s father Ben (Byron Jennings) matches his son with his dermatologist, Josh. The two go on a few dates and all seems to be going well. However, when they are ready to hook up, Michael is perturbed by Josh’s prodigious genitalia. In response, Josh (Peter Porte, Brad in Baby Daddy) whips out a syringe of Botox from the bedside table and assures Michael that the medical procedure, performed on Michael’s butthole, will facilitate receptive sex. Michael is surprised by this suggestion and expresses a number of reservations before hurriedly getting dressed and abandoning the encounter altogether.
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It turns out that injecting Botox into the butthole is a legitimate medical practice. Anal Botox treatments are provided for certain medical concerns, such as anal fissures and incontinence. It is also practiced for cosmetic purposes, often on gay men and postpartum individuals to provide so-called «anal rejuvenation,» comparable to vaginal rejuvenation. People do also get Botox in the butthole to
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