There's no Supernatural without Sam and Dean Winchester… apart from that one time. Supernatural lore is jam-packed with colorful characters of all specimens and species - angels, demons, children of Lucifer who become gods, etc. Despite the likes of Bobby Singer, Crowley and Castiel all earning fan-favorite status, however, the Winchester brothers are undoubtedly Supernatural's beating heart. Even in episodes where Lebanon's most famous sons aren't the main focus (see season 13's «Wayward Sisters»), Sam and Dean are never too far from the action.
With that in mind, it's hardly surprising that both Jensen Ackles and Jared Padalecki feature in every single Supernatural episode. Across 15 seasons between 2005 and 2020 (that'll be a total of 327 episodes), neither actor skips a hunt. On occasions rarer than a successful Castiel pop culture reference, Supernatural has focused upon one brother over the other, but both leading men always appear somehow — even if only for a single scene. Supernatural season 4's «In The Beginning,» for instance, almost entirely comprises Dean and Castiel traveling back in time, and yet Jared Padalecki still shows his face briefly in the opening moments.
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A Supernatural episode without Jensen Ackles doesn't exist — but there is one story where Dean Winchester fails to appear: season 14's «Stranger In A Strange Land.» Dean Winchester reluctantly strikes a deal with Apocalypse World Michael in Supernatural season 13's finale, agreeing to serve as the archangel's vessel in exchange for enough power to kill Lucifer. As per those tragic terms, the season ends with Michael fully occupying Dean's body (and doing a regrettable Peaky
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