Although he had developed devastating weapons, Iron Man would never dream of deploying them. Unfortunately, that changed when he became evil. This happened in Superior Iron Man #8. The issue was written by Tom Taylor and illustrated by Yildiray Cinar.
During the blockbuster Marvel crossover events Axis, the alignment of various Marvel characters was switched. Most of the alignments were reverted by the end of the story, but Tony Stark managed to escape. He remained evil and relocated to San Francisco, where he planned on charging the population absurd amounts of money for Extremis 3.0. He called it an app that allowed people to be the best versions of themselves. In reality, it was a virus he'd been feeding people through the water supply.
Related: Iron Man Would Have Created an Avengers Icon If He Never Built His Armor
Eight years before the story took place, Tony Stark had copied a digital version of his consciousness. Pepper Potts activated this consciousness in order to take on the evil Stark, who had donned a silver symbiote-based armor called the Endo-Sym. To battle this digital version of himself, the evil Stark deployed a weapon he had previously devised called Bio-Mark-One. The concept was to use electrical impulses to take over the minds and bodies of people to use as drones on the battlefield. Instead, Stark used the Extremis 3.0 to deploy this technology on the population of San Francisco, essentially turning them into a mind-controlled human shield.
Out of all the crazy things Tony Stark did throughout the Superior Iron Man series, this is probably the scariest. It's inherently terrifying not just because of the act itself but because of what it represents ideologically for Tony Stark. He did not develop the
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