In the current landscape of Dragon Ball continuity, Goku has become so powerful that he is able to channel god-like energy with which he is able to use to defeat even the strongest mortal foe, but he is still no match for the God of Destruction, Lord Beerus. However, there is another earthbound fighter who had one ability Goku could never attain, and with that power, could have defeated Beerus in a matter of seconds. Unfortunately, Goku accidentally killed him.
Lord Beerus made his first appearance in Dragon Ball Super Chapter 1 by Akira Toriyama and Toyotarou. In the chapter, Beerus is searching for a being that was prophesied to eventually kill him, a being known as a Super Saiyan God. So, Beerus tracks down the few remaining Saiyans left in the universe, and one of them was on King Kai’s world—a Saiyan named Goku. When Beerus meets Goku he is entirely unimpressed even when Goku powers up to Super Saiyan 3. To defeat him, Beerus simply flicks Goku on the forehead with so much force, that Goku is practically incapacitated after suffering a single, effortless blow.
Related: Krillin is Actually a Better Fighter Than Goku (For A Surprise Reason)
In Dragon Ball Chapter 51 by Akira Toriyama, Goku is battling Master Roshi in a world martial arts tournament for a chance to be named the greatest fighter on the planet. However, in the middle of their fight, Goku transforms into a Great Ape under the light of the full moon and goes absolutely berserk, destroying the arena and nearly killing everyone in the vicinity. To stop the rampage, Roshi uses a Kamehameha blast to destroy the moon, thereby stripping Goku of his Great Ape power and returning him to normal. While that was a solid, if not a bit over-the-top solution, Roshi–and
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